BDBM50537938 CHEMBL4642293

SMILES CCCCc1nc2c(N)nc3cc(OC)ccc3c2n1CC(C)(C)O

InChI Key InChIKey=OQZJBCNCOMTKHL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537938   

TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50537938(CHEMBL4642293)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK-Blue cells assessed as induction of NFkappaB activation by measuring increase in SEAP level by SEAP r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50537938(CHEMBL4642293)
Affinity DataEC50:  81nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as induction of NFkappaB activation by measuring increase in SEAP level by SEAP r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed