BDBM50537286 CHEMBL4483646

SMILES CN(C)CCOc1cc(ccc1NC(=O)C1COc2ccc(F)cc2C1)-c1ccncc1

InChI Key InChIKey=MLSJLNVTEFJNLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537286   

TargetRho-associated protein kinase 1(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537286(CHEMBL4483646)
Affinity DataIC50: 104nMAssay Description:Inhibition of ROCK1 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50537286(CHEMBL4483646)
Affinity DataIC50: 7nMAssay Description:Inhibition of ROCK2 (unknown origin) using STK2 as substrate measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed