BDBM50536563 CHEMBL4559801

SMILES CC(C)N1CCN(CC1)c1ccc(cn1)-c1cc(C(=O)NCc2c(cc(C)[nH]c2=O)C(C)C)c2cnn(C(C)C)c2c1

InChI Key InChIKey=KWNRYBPYSUPDNI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50536563   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50536563(CHEMBL4559801)
Affinity DataIC50: 10nMAssay Description:Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone-lysine N-methyltransferase EZH1(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50536563(CHEMBL4559801)
Affinity DataIC50: 320nMAssay Description:Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as subs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed