BDBM50536418 CHEMBL4591875

SMILES [H][C@@]12CC=C(n3cnc4ccccc34)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)n1ccnc1

InChI Key InChIKey=LKIKZGJOIUJYGD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50536418   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536418(CHEMBL4591875)
Affinity DataIC50: 480nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536418(CHEMBL4591875)
Affinity DataEC50:  190nMAssay Description:Inhibition of DHT-induced androgen receptor transactivation in human LNCaP cells after 24 hrs by luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed