BDBM50535885 CHEMBL4586770

SMILES [H][C@@]12Cc3cc(OC)c(OC)cc3[C@H](N1C(=O)\C(NC2=O)=C\c1ccc(OC)c(OC)c1)c1ccccc1

InChI Key InChIKey=NOZNNAVKRHBFLF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535885   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
National Research Council

Curated by ChEMBL
LigandPNGBDBM50535885(CHEMBL4586770)
Affinity DataEC50:  1.59E+4nMAssay Description:Agonist activity at recombinant rat TRPM8 expressed in HEK293 cells assessed as increase in intracellular calcium accumulation by Fluo-4-AM probe-bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
National Research Council

Curated by ChEMBL
LigandPNGBDBM50535885(CHEMBL4586770)
Affinity DataIC50: 1.28E+4nMAssay Description:Antagonist activity at recombinant rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium accumulation pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed