BDBM50535767 CHEMBL4473243

SMILES Cc1c(COc2cccc(OCc3cncc(c3)C#N)c2)cccc1-c1cccc(COc2ccc(CN[C@H](CO)C(O)=O)c(OCc3cncc(c3)C#N)c2)c1C

InChI Key InChIKey=WEPFUYDCOJPPBI-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535767   

TargetProgrammed cell death 1 ligand 1(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50535767(CHEMBL4473243)
Affinity DataKd:  3.70nMAssay Description:Binding affinity to FC-tagged human PDL1 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50535767(CHEMBL4473243)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human PDL1 expressed in CHO-K1 cells co-expressing aAPC assessed as reduction in PDL1 interaction with human PD1 expressed in Jurkat T ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed