BDBM50535627 CHEMBL4542052

SMILES COC(CC(C)C)c1ccc2ccc(-c3ccc(CC(Cc4ccc(cc4)C(F)(F)P(O)(O)=O)(c4ccccc4)n4nnc5ccccc45)cc3)c(c2n1)P(O)(O)=O

InChI Key InChIKey=ABRZBKRUFDGIHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535627   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50535627(CHEMBL4542052)
Affinity DataIC50: 5nMAssay Description:Inhibition of human FLAG-tagged PTP1B catalytic domain (1 to 298) expressed in Escherichia coli using fluorescein diphosphate as substrate by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50535627(CHEMBL4542052)
Affinity DataIC50: 36nMAssay Description:Inhibition of human FLAG-tagged TCPTP (1 to 296) expressed in Escherichia coli using fluorescein diphosphate as substrate by fluorescence based metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed