BDBM50535448 CHEMBL4469983

SMILES Cc1n[nH]c(=O)c(C)c1-c1ccc(Oc2nccc3occc23)cc1F

InChI Key InChIKey=YODCDZCSGNUYOR-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50535448   

TargetD(1A) dopamine receptor(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50535448(CHEMBL4469983)
Affinity DataEC50:  10nMAssay Description:Agonist activity at wild type human D1R expressed in HEK293 cells assessed as effect on cAMP accumulation incubated for 10 mins by Gs-cAMP Glosensor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50535448(CHEMBL4469983)
Affinity DataEC50:  490nMAssay Description:Agonist activity at wild type human D1R expressed in HEK293 cells assessed as effect on beta-arrestin2 recruitment by PRESTO-Tango beta-arrestin2 rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50535448(CHEMBL4469983)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human D1 receptor stably expressed in HEK293 cells assessed as induction of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50535448(CHEMBL4469983)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-SCH23390 from wild type human D1R expressed in HEK293 cell membranes incubated for 90 mins by scintillation counting based compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed