BDBM50535414 CHEMBL4463334

SMILES [H][C@]12O[C@H](O[C@@]1([H])[C@@H](O[C@@H]2COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1cnc2c(N)ncnc12)c1ccccc1

InChI Key InChIKey=BCGDNNLMSKVHGV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50535414   

TargetP2X purinoceptor 2(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2X2R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 611nMAssay Description:Antagonist activity at human P2X3R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 8.53E+3nMAssay Description:Antagonist activity at human P2X7R transfected in human 1321N1 cells assessed as inhibition of Bz-ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Mouse)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at -65 mV holding p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50535414(CHEMBL4463334)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at human P2X4R transfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed