BDBM50534415 CHEMBL4464764

SMILES c1cc(cc(c1)O)C2=C(C(=O)c3cc(ccc3O2)O)O

InChI Key InChIKey=LRMWPUURCIXKOC-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50534415   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 9.93E+4nMAssay Description:Inhibition of human ERG in membranes incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human microsomal CYP2D6 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human microsomal CYP2C9 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human microsomal CYP2C19 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human microsomal CYP3A4 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human microsomal CYP1A2 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DHFR using folic aid as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed