BDBM50534264 CHEMBL4465069

SMILES OC(=O)c1ccc(cc1)-c1ccc(\C=C2\NC(=O)N(Cc3ccccc3F)C2=O)o1

InChI Key InChIKey=BACDMNWGHOEOCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50534264   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534264(CHEMBL4465069)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-32P-labeled N14Y DNA substrate incubated for 15 mins by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50534264(CHEMBL4465069)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human recombinant TDP2 using 18-mer single stranded 5'-32P-labeled cordycepin DNA substrate incubated for 15 mins by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed