BDBM50532737 CHEMBL4447506

SMILES Cc1c(C)c(=O)oc2cc(OCC3CCCN(Cc4cccc(Cl)c4)C3)ccc12

InChI Key InChIKey=DVHSQXOMDRSHCZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50532737   

TargetAmine oxidase [flavin-containing] A(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50532737(CHEMBL4447506)
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant MAOA expressed in microsomes of baculovirus-infected insect cell using kynuramine as substrate preincubated for 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50532737(CHEMBL4447506)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant MAOB expressed in microsomes of baculovirus-infected insect cell using kynuramine as substrate preincubated for 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50532737(CHEMBL4447506)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50532737(CHEMBL4447506)
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant MAOA expressed in microsomes of baculovirus-infected insect cell using kynuramine as substrate preincubated for 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50532737(CHEMBL4447506)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant MAOB expressed in microsomes of baculovirus-infected insect cell using kynuramine as substrate preincubated for 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50532737(CHEMBL4447506)
Affinity DataIC50: 4.69E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50532737(CHEMBL4447506)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50532737(CHEMBL4447506)
Affinity DataIC50: 4.69E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed