BDBM50532283 CHEMBL4556129

SMILES CCn1cc(-c2nc3cc(Br)c(cc3n2C)C(=O)N2CCO[C@H]([C@@H]2CO)c2ccc(F)cc2)c2ccc(cc12)C#N

InChI Key InChIKey=YWMAQKQMUXYMAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532283   

Target2',5'-phosphodiesterase 12(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50532283(CHEMBL4556129)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human PDE12 (17 to 609 residues) expresssed in Escherichia coli BL21(DE3) cells using 2-5A as substrate assessed as AMP monomers and AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target2',5'-phosphodiesterase 12(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50532283(CHEMBL4556129)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human PDE12 (17 to 609 residues) expresssed in Escherichia coli BL21(DE3) cells using 2-5A as substrate assessed as AMP monomers and AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed