BDBM50532267 CHEMBL131355

SMILES CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3cccc(I)c3)C(=O)CCC2)cc1

InChI Key InChIKey=QNURTFDBHAQRSI-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532267   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532267(CHEMBL131355)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human His-tagged PDE3B catalytic domain expressed in Escherichia coli BL21(DE3) pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532267(CHEMBL131355)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human His-tagged PDE3B catalytic domain expressed in Escherichia coli BL21(DE3) pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)