BDBM50531753 CHEMBL4476000

SMILES Cn1cc(cn1)-c1ccc(Cn2cc(nn2)-c2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=PBYFXEFTMBEMLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50531753   

TargetVascular endothelial growth factor receptor 2(Human)
The First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50531753(CHEMBL4476000)
Affinity DataIC50: 58nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
The First Affiliated Hospital of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50531753(CHEMBL4476000)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Tie-2 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed