BDBM50531298 CHEMBL4592514

SMILES Fc1ccc(CNC(=O)Cn2cc(-c3ccccc3)c3ncn(C4CC4)c(=O)c23)cc1

InChI Key InChIKey=RTZBBWUBSYPHTL-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50531298   

TargetAdenosine receptor A1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531298(CHEMBL4592514)
Affinity DataIC50: 2.82E+3nMAssay Description:Antagonist activity at human A1AR expressed in CHO-K1 cells assessed as reduction in NECA-induced inhibition of forskolin-stimulated cAMP accumulatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531298(CHEMBL4592514)
Affinity DataIC50: 2.82E+3nMAssay Description:Antagonist activity at human A1AR expressed in CHO-K1 cells assessed as reduction in NECA-induced inhibition of forskolin-stimulated cAMP accumulatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531298(CHEMBL4592514)
Affinity DataKi:  589nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in CHO cells incubated for 50 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531298(CHEMBL4592514)
Affinity DataKi:  589nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in CHO cells incubated for 50 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531298(CHEMBL4592514)
Affinity DataKi:  3.63E+4nMAssay Description:Displacement of [3H]ZM241385 from human A2AR expressed in CHO cells after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531298(CHEMBL4592514)
Affinity DataKi:  3.63E+4nMAssay Description:Displacement of [3H]ZM241385 from human A2AR expressed in CHO cells after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed