BDBM50530609 CHEMBL4461010

SMILES C[C@H](NC(=O)[C@H](CC(=O)N1CCCC[C@@H]1C)NC(=O)c1cc(C)on1)C(=O)NCc1ccc(F)cc1F

InChI Key InChIKey=XOTJQAONWIKZEB-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50530609   

TargetProteasome subunit beta type-8(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50530609(CHEMBL4461010)
Affinity DataIC50: 26nMAssay Description:Inhibition of human 20S proteasome subunit beta-5i using Ac-ANW-AMC as substrate and measured every 30 secs for 30 mins by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50530609(CHEMBL4461010)
Affinity DataIC50: 26nMAssay Description:Inhibition of human 20S proteasome subunit beta-5i using Ac-ANW-AMC as substrate and measured every 30 secs for 30 mins by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50530609(CHEMBL4461010)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human 20S proteasome beta-5c subunit using Suc-LLVY-AMC as substrate and measured every 30 secs for 30 mins by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50530609(CHEMBL4461010)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human 20S proteasome beta-5c subunit using Suc-LLVY-AMC as substrate and measured every 30 secs for 30 mins by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed