BDBM50530385 CHEMBL4472802

SMILES CNC(=O)c1cnc(Nc2ccc(cn2)N2CCOCC2)cc1Nc1ccccc1S(C)(=O)=O

InChI Key InChIKey=SLYPRMCRZILHIR-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50530385   

LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 59nMAssay Description:Inhibition of TYK2/JAK1 in IFNalpha-stimulated human Kit225 cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 59nMAssay Description:Inhibition of TYK2/JAK1 in IFNalpha-stimulated human Kit225 cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 71nMAssay Description:Inhibition of TYK2/JAK2 in IL23-stimulated human Kit225 cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 58nMAssay Description:Inhibition of TYK2 JH2 domain in human whole blood assessed as inhibition of IFNalpha-induced STAT5 phosphorylation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of cKIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 58nMAssay Description:Inhibition of TYK2 JH2 domain in human whole blood assessed as inhibition of IFNalpha-induced STAT5 phosphorylation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of cKIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50530385(CHEMBL4472802)
Affinity DataIC50: 71nMAssay Description:Inhibition of TYK2/JAK2 in IL23-stimulated human Kit225 cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed