BDBM50529722 CHEMBL4582464

SMILES CC(C(=O)N1c2ccccc2CCc2ccccc12)n1nnc(n1)-c1ccc(cc1)N1CCOCC1

InChI Key InChIKey=YMNKISWXJOBEFZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529722   

TargetCysteine proteinase falcipain 3(Plasmodium falciparum (isolate 3D7))
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50529722(CHEMBL4582464)
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of Plasmodium falciparum falcipain-3 preincubated for 30 mins followed by Z-Leu-Arg-AMC substrate addition and measured up to 15 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50529722(CHEMBL4582464)
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 preincubated for 30 mins followed by Z-Leu-Arg-AMC substrate addition and measured up to 15 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCysteine proteinase falcipain 3(Plasmodium falciparum (isolate 3D7))
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50529722(CHEMBL4582464)
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of Plasmodium falciparum falcipain-3 preincubated for 30 mins followed by Z-Leu-Arg-AMC substrate addition and measured up to 15 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50529722(CHEMBL4582464)
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 preincubated for 30 mins followed by Z-Leu-Arg-AMC substrate addition and measured up to 15 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed