BDBM50529354 CHEMBL4441045

SMILES C[C@H](NC(=O)C1CCOCC1)c1ccc(NC(=O)N2CC(C2)c2ccc(N)nc2)cc1

InChI Key InChIKey=NACADUGWLZCXNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529354   

TargetCytochrome P450 3A4(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50529354(CHEMBL4441045)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using midazolam as substrate incubated for 40 to 130 mins in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed