BDBM50529246 CHEMBL4473654

SMILES NC(=N)NC(=O)c1nc(-c2cc3ccccc3o2)c(N)nc1N

InChI Key InChIKey=ZKLNPUKNSARQMG-UHFFFAOYSA-N

Data  1 KI  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50529246   

TargetVitamin K-dependent protein C(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of activated protein C (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of trypsin (unknown origin) using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor XI(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor 11a (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of tissue-type plasminogen activator (unknown origin) using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 430nMAssay Description:Inhibition of human kidney uPA using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 430nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor Xa (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of plasmin (unknown origin) using chromogenic H-D-Ile-L-propyl-L-arginine-p-nitroaniline as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of mouse uPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529246(CHEMBL4473654)
Affinity DataKi:  302nMAssay Description:Inhibition of human kidney uPA using fluorogenic Z-Pyr-Gly-Arg-MCA as substrate measured after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed