BDBM50529032 CHEMBL4454858

SMILES CCn1ccc(cc1=O)-c1cnc(N)c(O[C@H](C)c2c(Cl)ccc(F)c2Cl)c1

InChI Key InChIKey=IGHVDHNORPFTMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529032   

TargetALK tyrosine kinase receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529032(CHEMBL4454858)
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ALK L1196M mutant (1058 to 1620 residues) expressed in baculovirus expression system using Srct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529032(CHEMBL4454858)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) expressed in baculovirus expression system using Srctide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed