BDBM50528389 CHEMBL4534324

SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](OCc1ccc(Cl)cc1)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

InChI Key InChIKey=UDDUGXMYFCMHJO-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50528389   

TargetGlucocorticoid receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50528389(CHEMBL4534324)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in CHO-K1 cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50528389(CHEMBL4534324)
Affinity DataEC50:  1.89E+3nMAssay Description:Agonist activity at human androgen receptor in human LNCAP cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50528389(CHEMBL4534324)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human androgen receptor in human LNCAP cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50528389(CHEMBL4534324)
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity at human progesterone receptor expressed in CHO-K1 cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed