BDBM50526963 CHEMBL4456922

SMILES CC1=CC(=CN(C1=O)C)c2nc3ccccc3n2CC4CCOCC4

InChI Key InChIKey=IWELMDBRVJWCNU-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526963   

TargetBromodomain adjacent to zinc finger domain protein 2A(Human)
Gsk

Curated by ChEMBL

LigandBDBM50526963(CHEMBL4456922)Copy SMILESCopy InChI

Affinity DataIC50: 316nMAssay Description:Inhibition of BAZ2A (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetBromodomain-containing protein 4(Human)
Gsk

Curated by ChEMBL

LigandBDBM50526963(CHEMBL4456922)Copy SMILESCopy InChI

Affinity DataIC50: 79nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL