BDBM50526795 CHEMBL4450322

SMILES CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)[nH]nc2C1(C)C)c1ccccc1

InChI Key InChIKey=KPABJHHKKJIDGX-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50526795   

TargetCyclin-dependent kinase 7(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50: 53nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) pre incubated up to 60 mins followed by substrate and ATP additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50526795(CHEMBL4450322)
Affinity DataIC50: 54nMAssay Description:Inhibition of CDK7 (unknown origin) in human HAP1 cells incubated for 6 hrs by Western blot based competitive pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed