BDBM50526579 CHEMBL4442766

SMILES [H][C@@]12COP([O-])(=O)O[C@@]1([H])[C@@H](O)[C@@H](O2)n1cc(Br)c2c(N)ncnc12

InChI Key

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50526579   

TargetCyclic nucleotide-gated olfactory channel(Rat)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526579(CHEMBL4442766)
Affinity DataEC50:  120nMAssay Description:Activation of recombinant rat CNGA2/CNGA4/CNGB1b heterotetramer expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526579(CHEMBL4442766)
Affinity DataEC50:  2.36E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to DEP domain deficient mouse EPAC2 (280 to 988 residues) measured after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526579(CHEMBL4442766)
Affinity DataEC50:  2.54E+3nMAssay Description:Inhibition of 8Fluo-cAMP binding to recombinant human His-tagged EPAC1 (157 to 881 residues) expressed in Escherichia coli measured after 5 mins by f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclic nucleotide-gated olfactory channel(Rat)
University Hospital Jena

Curated by ChEMBL
LigandPNGBDBM50526579(CHEMBL4442766)
Affinity DataEC50:  540nMAssay Description:Activation of recombinant rat CNGA2 expressed in Xenopus laevis oocyte assessed as increase in current amplitude by patch-clamp electrophysiology met...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed