BDBM50526263 CHEMBL4475547

SMILES Cl.OC(=O)C1CCCN(CCO\N=C\c2ccccc2-c2ccc(F)cc2F)C1

InChI Key InChIKey=LZIXNZSPFWXFMF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526263   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526263(CHEMBL4475547)
Affinity DataIC50: 85nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526263(CHEMBL4475547)
Affinity DataKi:  14nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed