BDBM50526233 CHEMBL4574047

SMILES Nc1cc(cn(Cc2ccc(Cl)c(Cl)c2)c1=O)C(=O)Nc1cnn(c1)C1CCNC1

InChI Key InChIKey=XAEYDXSVMBFJOW-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526233   

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526233(CHEMBL4574047)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526233(CHEMBL4574047)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed