BDBM50526226 CHEMBL4559691

SMILES Cn1cc(NC(=O)c2cn(Cc3ccc(Cl)c(Cl)c3)c(=O)c3cnc(cc23)N2CCNCC2)cn1

InChI Key InChIKey=ZEVIDIAVNXOTJB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526226   

TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526226(CHEMBL4559691)
Affinity DataIC50: 630nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFascin(Human)
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526226(CHEMBL4559691)
Affinity DataKd:  580nMAssay Description:Binding affinity to human fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed