BDBM50525972 CHEMBL4459887

SMILES Oc1ccc(F)c(C(=O)c2ccc(s2)-c2cccc(NS(=O)(=O)c3ccccc3)c2)c1Cl

InChI Key InChIKey=XSBGMNVHRLMVIZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50525972   

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525972(CHEMBL4459887)
Affinity DataIC50: 16nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525972(CHEMBL4459887)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525972(CHEMBL4459887)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed