BDBM50525744 CHEMBL4555782

SMILES COc1ccc2c(CCNc3nc(NCc4ccc(=O)[nH]c4)c4nc[nH]c4n3)c[nH]c2c1

InChI Key InChIKey=FYNQORHKRPUAMT-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50525744   

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525744(CHEMBL4555782)
Affinity DataIC50: 741nMAssay Description:Inhibition of IP6K1 (unknown origin) incubated for 30 mins using IP6 as substrate in presence of ATP by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInositol hexakisphosphate kinase 3(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525744(CHEMBL4555782)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of IP6K3 (unknown origin) incubated for 120 mins using IP6 as substrate in presence of ATP by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525744(CHEMBL4555782)
Affinity DataIC50: 750nMAssay Description:Inhibition of IP6K1 (unknown origin) incubated for 30 mins using IP6 as substrate in presence of ATP by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInositol hexakisphosphate kinase 2(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525744(CHEMBL4555782)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of IP6K2 (unknown origin) incubated for 30 mins using IP6 as substrate in presence of ATP by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525744(CHEMBL4555782)
Affinity DataKi:  200nMAssay Description:Inhibition of IP6K1 (unknown origin) in presence of ATP at Km concentration by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInositol hexakisphosphate kinase 2(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525744(CHEMBL4555782)
Affinity DataKi:  4.88E+3nMAssay Description:Inhibition of IP6K2 (unknown origin) in presence of ATP at Km concentration by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInositol hexakisphosphate kinase 3(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50525744(CHEMBL4555782)
Affinity DataKi:  9.62E+3nMAssay Description:Inhibition of IP6K3 (unknown origin) in presence of ATP at Km concentration by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed