BDBM50525412 CHEMBL4516635

SMILES COc1cc2c(Nc3ccc(NC(=O)C(N4Cc5ccccc5C4=O)c4ccccc4)cc3F)ncnc2cc1OCC1CCN(C)CC1

InChI Key InChIKey=GOHVFUOAZCLZMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525412   

TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525412(CHEMBL4516635)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant human C-terminal His-tagged/N-terminal GST-tagged EGFR (668 to 1210 residues) T790M/L858R/C797S mutant expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed