BDBM50524578 CHEMBL4514617::US10980809, Example 18
SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)cc3)c2c2OCCOc12
InChI Key InChIKey=XROVNERVLRWCAV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50524578
TargetVascular endothelial growth factor receptor 2(Human)
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Beijing University of Technology
Curated by ChEMBL
Beijing University of Technology
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:1. Dilution of the compound: a total of 12 concentrations were obtained using a 4-fold gradient dilution from the highest concentration of 10000 nM (...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Beijing Scitech-Mq Pharmaceuticals
US Patent
Beijing Scitech-Mq Pharmaceuticals
US Patent
Affinity DataIC50: 275nMAssay Description:1. Preparation of test compounds: according to the molecular weight of the compounds, an appropriate volume of DMSO was directly added to dissolve th...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:1. Preparation of test compounds: according to the molecular weight of the compounds, an appropriate volume of DMSO was directly added to dissolve th...More data for this Ligand-Target Pair