BDBM50524487 CHEMBL1232596

SMILES Nc1nc2ccccc2nc1N1CCCC1

InChI Key InChIKey=LWWDIFFPFOZSSB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524487   

TargetOxidized purine nucleoside triphosphate hydrolase(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50524487(CHEMBL1232596)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50524487(CHEMBL1232596)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)