BDBM50524095 CHEMBL4532985

SMILES O=C(NC1=Nc2ccccc2C2=NCCN12)c1cccnc1

InChI Key InChIKey=JTBKRVKNIZKKRD-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524095   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University Park Nottingham

Curated by ChEMBL

LigandBDBM50524095(CHEMBL4532985)Copy SMILESCopy InChI

Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal His-tagged truncated human PI3Kgamma (deltaN 1 to 108 residues) after 2 hrs in presence of [33P]ATP by BetaPlate liquid scin...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University Park Nottingham

Curated by ChEMBL

LigandBDBM50524095(CHEMBL4532985)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His-tagged truncated human PI3Kbeta (deltaN 1 to 108 residues) after 2 hrs in presence of [33P]ATP by BetaPlate liquid scint...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL