BDBM50523289 CHEMBL4436095

SMILES Clc1ccc(cc1)C(=O)Cn1cc(COc2ccc(\C=C3/SC(=S)NC3=O)cc2)nn1

InChI Key InChIKey=SSOAVWNAOMKQNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523289   

TargetProstaglandin G/H synthase 2(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50523289(CHEMBL4436095)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant COX2 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50523289(CHEMBL4436095)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed