BDBM50523277 CHEMBL4516356

SMILES O=C(Nc1cc(COCc2cn(CCNc3c4CCCCc4nc4ccccc34)nn2)ccn1)Nc1cccc2C(=O)N3CCCCC3c12

InChI Key InChIKey=IDMGTGWKKYHBFA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50523277   

LigandPNGBDBM50523277(CHEMBL4516356)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50523277(CHEMBL4516356)
Affinity DataIC50: 10nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50523277(CHEMBL4516356)
Affinity DataIC50: 169nMAssay Description:Inhibition of human serum BChE using BTCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellman's me...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50523277(CHEMBL4516356)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed