BDBM50522905 CHEMBL4593715

SMILES Cc1cc(sc1S(=O)(=O)Nc1cc(ccc1Cl)C(F)(F)F)C(=O)NC[C@@H](O)c1ccccc1

InChI Key InChIKey=DWTFITNCBWXVTC-UHFFFAOYSA-N

Data  1 IC50  1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522905   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Forma Therapeutics

Curated by ChEMBL

LigandBDBM50522905(CHEMBL4593715)Copy SMILESCopy InChI

Affinity DataKd:  165nMAssay Description:Binding affinity to biotin-labelled TEV-fused GST-tagged MCl-1 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Forma Therapeutics

Curated by ChEMBL

LigandBDBM50522905(CHEMBL4593715)Copy SMILESCopy InChI

Affinity DataIC50: 149nMAssay Description:Inhibition of FITSI-labelled BID binding to human MCl-1 (171 to 327 residues) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization a...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL