BDBM50522778 CHEMBL4444043

SMILES Fc1ccc(cc1)C1C=C(Nc2nncn12)c1cccc2ccccc12

InChI Key InChIKey=MZJCAWCKWVXSLO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50522778   

TargetAmyloid-beta precursor protein(Human)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50522778(CHEMBL4444043)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation measured after 48 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50522778(CHEMBL4444043)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50522778(CHEMBL4444043)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of electric eel Ache using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed