BDBM50522288 CHEMBL4518527

SMILES OC(=O)Cn1cnc2c(NC(=O)c3cccc(c3)-c3ccccc3)ncnc12

InChI Key InChIKey=HKHQUFVPYZFWFY-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50522288   

Target5'-nucleotidase(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50522288(CHEMBL4518527)
Affinity DataKi:  8.43E+5nMAssay Description:Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
Target5'-nucleotidase(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50522288(CHEMBL4518527)
Affinity DataKi:  9.95E+5nMAssay Description:Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
Target5'-nucleotidase(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50522288(CHEMBL4518527)
Affinity DataKi:  1.65E+6nMAssay Description:Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
Target5'-nucleotidase(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50522288(CHEMBL4518527)
Affinity DataKi:  1.13E+7nMAssay Description:Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for enzyme substrate complex using varying level of IMP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
Target5'-nucleotidase(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50522288(CHEMBL4518527)
Affinity DataKi:  2.52E+6nMAssay Description:Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed