BDBM50522116 CHEMBL4522393

SMILES [H][C@]12Oc3c4c(C[C@@H](N(CC5CC5)S(=O)(=O)c5ccccc5)[C@]([H])(CC[C@@H]1N(C)C(=O)\C=C\c1ccoc1)[C@]24[H])ccc3OC

InChI Key InChIKey=VTGLFMAGTSQXRC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522116   

TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50522116(CHEMBL4522393)
Affinity DataKi: >10nMAssay Description:Antagonist activity at human OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincubated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50522116(CHEMBL4522393)
Affinity DataKi: >10nMAssay Description:Antagonist activity at human OX1R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincubated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed