BDBM50521718 CHEMBL4587426
SMILES [H][C@]12C[C@]1([H])N([C@@H](C2)c1nc2ccc3cc-4c(OCc5cc(ccc-45)-c4cnc([nH]4)[C@@H]4C[C@H](COC)CN4C(=O)[C@H](NC(=O)OC)c4ccccc4)cc3c2[nH]1)C(=O)[C@@H](NC(=O)OC)C(C)C
InChI Key InChIKey=TYKRKURWQMJOHX-UHFFFAOYSA-N
Data 7 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50521718
Affinity DataEC50: 0.0180nMAssay Description:Inhibition of NS5A in HCV genotype 3a S52 infected in human HuH7 transient chimeric replicon cells assessed as reduction in viral replication after 3...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0110nMAssay Description:Inhibition of NS5A in HCV genotype 1b Con1 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luciferas...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00600nMAssay Description:Inhibition of NS5A in HCV genotype 2a JFH1 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luciferas...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0460nMAssay Description:Inhibition of NS5A in HCV genotype 2b MD2b-1 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lucifer...More data for this Ligand-Target Pair
Affinity DataEC50: 0.113nMAssay Description:Inhibition of NS5A L31M mutant in HCV genotype 2a J6 (M31) infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 d...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00900nMAssay Description:Inhibition of NS5A in HCV genotype 4a ED43 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luciferas...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0100nMAssay Description:Inhibition of NS5A in HCV genotype 1a H77 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luciferase...More data for this Ligand-Target Pair