BDBM50521712 CHEMBL4565239
SMILES COC[C@H]1C[C@H](N(C1)C(=O)[C@@H](NC(=O)OC)C(C)C)c1nc2ccc3cc-4c(OCc5cc(ccc-45)-c4cnc([nH]4)[C@@H]4CCCN4C(=O)[C@@H](NC(=O)OC)C(C)C)cc3c2[nH]1
InChI Key InChIKey=GXDGJFIBYNZDAU-UHFFFAOYSA-N
Data 17 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50521712
Affinity DataEC50: 0.0860nMAssay Description:Inhibition of NS5A Y93H mutant in HCV genotype 1b infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.135nMAssay Description:Inhibition of NS5A in HCV genotype 2b MD2b-1 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lucifer...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Inhibition of NS5A Q30E mutant in HCV genotype 1a infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0370nMAssay Description:Inhibition of NS5A in wild type HCV genotype 1a infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luci...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00800nMAssay Description:Inhibition of NS5A L31M mutant in HCV genotype 2a JFH1 (M31) infected in human HuH7 replicon cells assessed as reduction in viral replication after 3...More data for this Ligand-Target Pair
Affinity DataEC50: 0.220nMAssay Description:Inhibition of NS5A Q30R mutant in HCV genotype 1a infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0140nMAssay Description:Inhibition of NS5A in HCV genotype 4a ED43 infected in human HuH7 transient chimeric replicon cells assessed as reduction in viral replication after ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0260nMAssay Description:Inhibition of NS5A in HCV genotype 1b Con1 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luciferas...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0210nMAssay Description:Inhibition of NS5A in HCV genotype 1a H77 infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luciferase...More data for this Ligand-Target Pair
Affinity DataEC50: 0.280nMAssay Description:Inhibition of NS5A L31M mutant in HCV genotype 2a J6 (M31) infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 d...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0260nMAssay Description:Inhibition of NS5A in wild type HCV genotype 1b infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by luci...More data for this Ligand-Target Pair
Affinity DataEC50: 4.70nMAssay Description:Inhibition of NS5A Y93H mutant in HCV genotype 1a infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.220nMAssay Description:Inhibition of NS5A Y93C mutant in HCV genotype 1a infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.370nMAssay Description:Inhibition of NS5A L31M mutant in HCV genotype 1a infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.150nMAssay Description:Inhibition of NS5A Q30H mutant in HCV genotype 1a infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.190nMAssay Description:Inhibition of NS5A M28T mutant in HCV genotype 1a infected in human HuH7 replicon cells assessed as reduction in viral replication after 3 days by lu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0240nMAssay Description:Inhibition of NS5A in HCV genotype 3a S52 infected in human HuH7 transient chimeric replicon cells assessed as reduction in viral replication after 3...More data for this Ligand-Target Pair