BDBM50520131 CHEMBL4588661

SMILES COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1

InChI Key InChIKey=PKONCIPMLLIAIL-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50520131   

TargetWD repeat-containing protein 5(Human)
Frederick National Laboratory For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50520131(CHEMBL4588661)
Affinity DataKd: <0.0200nMAssay Description:Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Frederick National Laboratory For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50520131(CHEMBL4588661)
Affinity DataKi: <0.0200nMAssay Description:Inhibition of N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells assessed as inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
Frederick National Laboratory For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50520131(CHEMBL4588661)
Affinity DataKi: <0.0200nMAssay Description:Inhibition of 6His-SUMO tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells incubated for 1 hr by TR-FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed