BDBM50519509 CHEMBL4473333

SMILES COc1ccc(cc1)-c1nc(NCCOc2ccc(\C=C\C(=O)NO)cc2)cc2c3ccccc3[nH]c12

InChI Key InChIKey=KEGIUBDGCWRWNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519509   

TargetHistone deacetylase 1(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50519509(CHEMBL4473333)
Affinity DataIC50: 75nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys (Ac)-AMC as substrate incubated for 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50519509(CHEMBL4473333)
Affinity DataIC50: 75nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys (Ac)-AMC as substrate measured after 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed