BDBM50519153 CHEMBL4460522

SMILES COc1cc(F)c(Cl)c2cc(C(=O)N[C@H](C)c3ccc(cc3)C(O)=O)n(C)c12

InChI Key InChIKey=FBOWPSNTGAWTNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519153   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50519153(CHEMBL4460522)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50519153(CHEMBL4460522)
Affinity DataIC50: 123nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed