BDBM50519143 CHEMBL4524921

SMILES Cn1nc(cc1C(=O)NC(C)(C)c1ccc(cc1)C(O)=O)-c1ccccc1

InChI Key InChIKey=LNNFZVSRSIQIPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519143   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50519143(CHEMBL4524921)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed