BDBM50519010 CHEMBL4592077

SMILES CN1[C@H](Cc2c[nH]c3c(CCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc4ccccc4)C1=O)cccc23)C(N)=O

InChI Key InChIKey=KDVWFGZFEJOVIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50519010   

TargetIntegrin alpha-V/beta-3(Human)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50519010(CHEMBL4592077)
Affinity DataIC50: 34nMAssay Description:Inhibition of human vitronectin binding to human integrin alphavbeta3 receptor after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50519010(CHEMBL4592077)
Affinity DataIC50: 154nMAssay Description:Inhibition of human fibronectin binding to human integrin alpha5beta1 incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50519010(CHEMBL4592077)
Affinity DataIC50: 5.00E+5nMAssay Description:Binding affinity to integrin alphavbeta3 receptor in human WM115 cells assessed as inhibition of cell adhesion to vitronectin after 0.5 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed