BDBM50518788 CHEMBL4454905::US20240279201, Compound FX1128

SMILES Cc1c(nnn1-c1ccccc1C)C(=O)Nc1ccc2ccccc2n1

InChI Key InChIKey=SXZFICNOPPNYJM-UHFFFAOYSA-N

Data  7 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50518788   

TargetGlycogen synthase kinase-3 beta(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to recombinant full length human N-terminal GST-tagged GSK3beta expressed in sf9 cells by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtein Wnt-3a(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human Wnt3a in HEK293 cells assessed as Wnt signalling by measuring reduction in relative luminescence units incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetCatenin beta-1/Protein Wnt-3a(Human)
University of Maryland at Baltimore

US Patent
LigandPNGBDBM50518788(CHEMBL4454905 | US20240279201, Compound FX1128)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent