BDBM50517239 CHEMBL4441401

SMILES C[C@H]1CN(CCN1c1ncnc2CC(CCc12)c1c(C)ccc2[nH]ncc12)C(=O)C=C

InChI Key InChIKey=MBPPZCHPUVJHGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517239   

TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517239(CHEMBL4441401)
Affinity DataIC50: 4.86E+3nMAssay Description:Inhibition of KRAS G12C mutant in human MIAPaCa2 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed